Creatine Monohydrate offers therapeutic benefits, including the prevention of ATP depletion, stimulation of protein synthesis and cell volumization. Creatine Monohydrate is the undisputed king of Creatine. Over 95% of all research ever conducted used Creatine Monohydrate. Other forms of Creatine have come and gone, all trying to make the claim that they have improved the original Creatine. The truth is that very few, if any, scientific studies are even being attempted to try to prove that they enhance performance in any way.